Antioxidant and cytoprotective properties of partridgeberry polyphenols.

Antioxidant, Cytoprotective and Neuroprotective Properties of Wild Partridgeberry of Southern Labrador

Partridgeberry polyphenols protect primary cortical and hippocampal neurons against β-amyloid toxicity.

β-Amyloid (Aβ) deposition elicits a toxic effect on neurons and plays a crucial role in the etiology and/or progression of Alzheimer's disease (AD). Polyphenols found in fruits are endorsed for nutritional intervention in AD, since they are known to have extensive therapeutic properties apropos of brain health owing to their anti-oxidative effects against Aβ and neural reactive oxygen species (...

Cytoprotective and antioxidant effects of Echium amoenum anthocyanin-rich extract in human endothelial cells (HUVECs)

Objective: Echium amoenum Fisch. & C.A. Mey. is used for the treatment of various diseases in traditional medicine. This plant is a major source of anthocyanins with beneficial cardiovascular properties such as anti-atherosclerotic and antihypertensive effects. In the present study, the protective and antioxidant effects of anthocyanin-rich E. amoenum extract were evaluated on human vascular en...

Polyphenols isolated from virgin coconut oil attenuate cadmium-induced dyslipidemia and oxidative stress due to their antioxidant properties and potential benefits on cardiovascular risk ratios in rats

Objective: Literature has confirmed the pathogenic role of cadmium (Cd) and its exposure in the induction of dyslipidemia implicated in the development and increasing incidence of cardiovascular diseases. The current study explored whether polyphenolics isolated from virgin coconut oil (VCO) prevent Cd-induced dyslipidemia and investigate the underlying mechanism of action, in rats. Materials a...

Antioxidant Effects of Pinus Eldarica Extracts Against Cisplatin-Induced Cytotoxicity in Human Hepatoma (Hepg2) Cell Line

Background:  Cisplatin has cytotoxic effects through free radical generation. Reports indicate that various members of Pinaceae family may have antioxidant properties. In this study we investigated the cytoprotective effects of needle volatile oil and bark extract of Pinus eldarica in hepatoma G2 (HepG2) cell line.  Methods: Using the maceration technique, we obtained the ethanolic extract of ...